The Transfers of a Day 3 Embryo Obtained from Women with Severe Diminished Oocyte Reserve with an Even Number of Blastomeres has A 5-Fold Greater Chance of Resulting in a Live Baby Compared to Cleavage Stage Embryos with an Uneven Number of Blastomeres
Jerome H Check*, Donna Summer MS, Danya Howarth MS, Michael Sobel DO and Kathy Hallahan RN
Abstract
A low level of blastomeres in a day 3 cleavage staged embryo is associated with lower live delivered pregnancy rates (LDPRs) compared to embryos with more blastomeres. The study presented here evaluated whether embryos with an odd number of blastomeres with a greater number of cells is less likely to lead to a live delivery than embryos with an even number of blastomeres. For the study, the women had marked diminished oocyte reserve (DOR) so that only 1 embryo was transferred on day 3. The LDPRs for woman with embryos that had 5, 7, 9 or 11 blastomeres was 2.4% per transfer vs 14.9%, for the women with 6, 8, 10, or 12 blastomeres. The patients were aged < 39 years. An embryo with an odd number of blastomeres is far less likely to achieve a live delivery compared to an even number of blastomeres in women < age 39 with marked DOR.
